[Toxicology Letters (1982): 14, 183]

Detoxification of cassava leaves by simple traditional methods.

Cassava leaves, which usually contain large quantities of cyanogenic glycosides, were processed into a Zairian traditional vegetable sauce "Mpondu" by simple methods which included blanching (10 min), mashing and then boiling for 20-80 min. These methods enhanced the detoxification of the leaves, with blanching alone resulting in the loss of 57% of the free (non-glycosidic) cyanide content and ...

Presence of two molecular weight forms of somatostatin in neurons from chick embryo cerebral hemispheres in culture.

Following its isolation hypothalamic extracts [l] the tetradecapeptide somatostatin (SS-14) has been found to be widely distributed throughout the central nervous system [2], the gastrointestinal tract and the pancreas [3]. Evidence for synthesis of SS-14 by cerebral cells in culture has also been reported (4,5]. We report here that neurons from chick embryo cerebral hemispheres, cultured in se...

Mutagenicity of 2,4,6-trinitrotoluene-surfactant complexes.

Embryotoxicity of 4-deoxynivalenol (vomitoxin) in mice.

Toxicology of chloral hydrate in the mouse.

Chloral hydrate has been found in our drinking water supplies at levels up to 5 micrograms/1. The purpose of this study was to evalute the acute and subchronic toxicology of chloral hydrate in the random-bred CD-1 mouse, to provide data for risk assessment. The acute oral LD50 of this compound was 1442 and 1265 mg/kg in male and female mice, respectively. Acute toxicity appeared to be related t...